doi: 10.1007/s00464-017-5467-3 32
The following phenomena were observed based on TEM analysis in group B: a large number of vacuoles in the cytoplasm, obvious oedema and cavitation of organelles, increased levels of abnormal lipids, rupture of the nuclear membrane of interstitial cells, mitochondrial oedema, partial absence of cytoplasm, increased nuclear heterochromatin, expansion of endoplasmic reticulum, obvious damage to the spermatogonia membrane, a few vacuoles near the membrane, endoplasm of primary spermatocytes, insignificant swelling of the endoplasmic reticulum, the lack of a defined cell membrane, increased nuclear heterochromatin and the formation of large vacuoles next to secondary spermatocytes
Deficiencies in vitamins B6, B9 (folate), or B12 lower antioxidant activity and increase harmful molecules like reactive oxygen species (ROS) and proinflammatory proteins
In animal studies, It has been found to reduce fat storage and change food preferences away from fatty foods [6, 7, 8]
Focus on Nutrition: Regardless of the medication, eating a protein-rich, nutrient-dense diet helps preserve muscle mass and supports your metabolism