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[DOI] [PubMed] [Google Scholar] 26.Rattanakaemakorn P, Phusuphitchayanan P, Pakornphadungsit K, Thadanipon K, Suchonwanit P
Although there is little evidence of neoantigen dissemination, the vaccine stimulates nave T cells to recognize immunogenic neoantigens instead of amplifying existing responses, highlighting its ability to surmount immunological tolerance in a malignancy with minimal mutational load, such as PDAC
The secondary structures of all peptides were assigned using DSSP software from their tertiary structure 43
This 16-amino-acid peptide, encoded by the mitochondrial 12S rRNA gene, is of growing interest in molecular biology for its role in studies involving cellular metabolism, AMPK activation, mitochondrial signalling, and metabolic regulation
TMAO is reported to be involved in vascular calcification and plaque instability, which are the key risk factors for malignant cardiovascular events (25)
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