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Safety, tolerability, and pharmacokinetics of casimersen in patients with duchenne muscular dystrophy amenable to exon 45 skipping: a randomized, double-blind, placebo-controlled, dose-titration trial

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After 48 weeks of treatment with olepotide, the average weight loss from baseline was as high as 19.3%, and the proportion of subjects who achieved a 25% weight loss was as high as 97.2%

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