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Since vitamin B12 absorption relies on adequate stomach acid to release it from food, long-term use of these medications may put you at increased risk of deficiency

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Have certain medical conditions: Problems that can restrict vitamin B12 absorption include pernicious anemia (a rare autoimmune disease that keeps the body from making a protein necessary to absorb B12), digestive illnesses, such as celiac and Crohns diseases, and immune disorders such as lupus, among others