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Hormonal shifts may play a part for women, too

Speliotes, E

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J Biol Chem 265:80018008 Nauck MA, Bartels E, Orskov C, Ebert R, Creutzfeldt W (1993a) Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations

However, CDK4/6 inhibitors do not suppress ferroptosis, suggesting that CDKN1A/p21 inhibits ferroptotic cell death through other unknown signaling pathways [131, 132]