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Many autoimmune conditions are linked to gut health, as increased intestinal permeability can allow toxins and undigested food particles to enter the bloodstream, potentially triggering immune responses

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The present review provides a comprehensive account of how the S-glutathionylation cycle influences protein structure/function and cellular regulatory events, and how these may impact on human diseases

GPX4 reduces one PL-OOH molecule to one alcohol molecule by using two GSH molecules as donors and produces GSSG, which can be converted to GSH with NADPH/H+ and glutathione reductase (Lin et al., 2020)

The transcription factor IFN regulatory factor-4 controls experimental colitis in mice via T cell-derived IL-6