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Description

P53 can inhibit cystine uptake by inhibiting the expression of SLC7A11, a vital component of the cystine/glutamate reverse transporter, thereby enhancing the sensitivity of cells to ferroptosis [32]

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[DOI] [PubMed] [Google Scholar] 137.Seiler A., Schneider M., Frster H., Roth S., Wirth E.K., Culmsee C., Plesnila N., Kremmer E., Rdmark O., Wurst W., et al

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