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NONSTEROIDAL ANTI-INFLAMMATORY DRUGS MECHANISM OF ACTION The nonsteroidal anti-inflammatory drugs comprise a large family of weak acidic drugs whose pharmacological effects result primarily from the inhibition of cyclooxygenase (COX) , an enzyme that catalyzes the first step in the synthesis of prostaglandins from arachidonic acid and other precursor fatty acids (see Chapter 26)

Likewise, physical barriers such as condoms and copper IUDs are also unaffected

HRT works by releasing estrogen into the bloodstream or vaginal tissue, and is available in many forms, including pills, patches, vaginal rings, pellets, and topical creams and gels

Woodhead Publishing, pp