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Figure 1 Discussion In the presented case of a newly diagnosed patient with type 2 diabetes, euDKA occurred at the very early onset after initiation of combined therapy with GLP-1RA and SGLT2i, in the absence of infection or other precipitating factors (such as alcohol overdose, pancreatitis, pregnancy), and proved refractory to standard therapy with insulin, glucose, and fluid resuscitation

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Overexpression of human IGF-I via direct rAAV-mediated gene transfer improves the early repair of articular cartilage defects in vivo

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