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Copper Peptide Products Versus Retinoids and Cosmetic Actives Cu-GHK has been compared with vitamin C and retinoic acid in a small collagen-production context summarized in a topical peptide review, where collagen increased in 70% of Cu-GHK-treated participants versus 50% with vitamin C and 40% with retinoic acid after one month [2]

It works, at least in part, by activating the FAKpaxillin pathway in cells

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Bell , J.G., MacKinlay , E.E., Dick, J.R., et al

Some mechanistic evidence suggests these may actually be anti-anabolic by suppressing mTOR pathways involved in muscle protein synthesis