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J Clin Invest (2017) 127:377083

PDK1 phosphorylates Akt at Thr308, and mTORC2 phosphorylates Akt at Ser473

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To report suspected adverse reactions to compounded tirzepatide, contact the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.In case of emergencies, call 911 or go to the nearest emergency room