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These include proton pump inhibitors and histamine H 2 blockers, which suppress gastric acid secretion and prevent release of vitamin B 12 from food.42 Other drugs like metformin reduces intestinal availability of free calcium ions for vitamin B 12 intrinsic factor complex uptake by ileal cell membrane receptors,43 and cholestyramine interferes with vitamin B 12 absorption from intestine.44 Clinical manifestations of vitamin B 12 deficiency Vitamin B 12 is essential for metabolism of all cells in our body

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The pleasant mango flavour makes it a practical choice for regular use, while the liquid format offers flexibility for those who prefer not to take capsules

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It is important to emphasise that these proposals are based almost entirely on preclinical data principally in vitro (cell culture) experiments and animal studies and have not been reliably demonstrated in robust human clinical trials: Stimulation of follicle enlargement: Laboratory studies suggest GHK-Cu may increase hair follicle size, potentially counteracting the miniaturisation associated with androgenetic alopecia (pattern hair loss), though this has not been confirmed in humans