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However, immune neutralization of GIP or removal of GIP from intestinal extracts does not completely eliminate the insulin-stimulating activity, indicating that there are other substances with insulin-stimulating activity in the intestine (Lopez et al., 1983

The distinction between cholangiofibrosis and this phenotype of cholangiocarcinoma is difficult and controversial and is primarily based on extent of liver involvement since unequivocal metastasis is rare

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