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For someone with diverticulosis, this increased transit time and the resulting pressure can be a significant concern

Expert Opin Investig Drugs 2011;20:549557.ArticlePubMed 56

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This increase was associated with a 1.5-fold increase in portal plasma GLP-1 upon gastric glucose stimulation in diet-induced obese VSG rats compared to diet-induced obese sham controls, suggesting that antral GLP-1 producing cells contribute significantly to portal GLP-1 (Ribeiro-Parenti et al., 2021)

Time Flexibility : You can take it any time of day, with or without food