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GLP-1 therapies may improve sleep for some while disrupting it for others through shifts in glucose patterns, appetite, or GI function

conversely, enhancing BCAA catabolism through pharmacological or dietary interventions may improve insulin sensitivity (141).Meta-analyses have shown that for elderly T2DM patients with sarcopenia, BCAA supplementation may improve body composition (142)

Age, comorbidities, and medication tolerance all factor into provider decision-making

Further, none of the assessments beyond 26 weeks were controlled for multiplicity, which creates further uncertainty around these findings

[DOI] [PubMed] [Google Scholar] 89.Wong G., Garner E.M., Srivastava G