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In addition, nearly 90% to 95% of the population in the region has type 2 diabetes, and it frequently develops among people aged more than 45 years, thereby enhancing the market growth and demand globally

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Overall, across the two repeat experiments for Cagri and CagriBB bound to the CTR, the conformational equilibrium between the bypass vs CT-like state was similar, suggesting that the salt bridge/ionic lock is sufficient to preferentially stabilize the bypass conformation at CTR (Supplementary Fig