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Given the crucial role of LRRK2 in cellular autophagy and the extensive literature linking PD-associated mutations of LRRK2 to impaired autophagy and abnormality in the lysosomal pathway 20,21,22 , we labeled autophagosomes and lysosomes in SN TH neurons by using p62 and LAMP1 staining

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A vitamin B12 deficiency can cause a wide range of severe symptoms, such as fatigue, depression, nerve damage, muscle weakness, joint pain and difficulties with balance

As people grow older, the body's natural antioxidant stores are depleted and overall health and wellness can suffer