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[DOI] [PMC free article] [PubMed] [Google Scholar] 152.Ujueta F, Arenas IA, Escolar E, Diaz D, Boineau R, Mark DB, Golden P, Lindblad L, Kim H, Lee KL, Lamas GA

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Intranasal delivery, used with Selank and Semax, bypasses first-pass enzymatic metabolism in some systems, which partially explains why researchers observe longer effective durations than the IV values listed in typical half-life reference data