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In subsequent experiments involving deeper burns (direct flame for 7 s), BPC-157 creams (50 microg, 5 microg, 500 ng, 50 ng, or 5 ng of BPC 157 dissolved in 2 ml of distilled water was mixed with 50 g of commercial neutral cream), or vehicle as a thin layer of cream, were applied topically at the burn site

Native amylin has a half-life of approximately 2-4 minutes in biological systems

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A far cry from what injectable or oral formulations of BPC-157 are capable of producing

The peptide's effects also accumulate over time, with metabolic improvements progressing over weeks as NAD+-dependent adaptations develop