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Front Mol Biosci

In addition, it has been discovered that a metabolic shift toward fatty acid oxidation, necessary for tumor lymph node metastasis, occurs in tumor cells

The decreased expression of TF in oligodendrocytes in the SN of PD patients may decrease the ability of oligodendrocytes to sequester excess iron, ultimately resulting in an increase in oxidative stress in dopaminergic neurons

In controlled laboratory settings, GLP-1 receptor activation has been associated with: Reductions in alcohol intake Decreased opioid-seeking behaviors Lower rates of binge-like consumption patterns However, findings from animal models do not always translate directly to human outcomes