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This vitamin is excreted through bile, and is reabsorbed in the enterohepatic circulation

A 90-person Indonesian multicentre trial testing oral glutathione plus vitamin C, alpha-lipoic acid, and zinc over 12 weeks in participants with Fitzpatrick IV and V skin types, a melanin range broadly similar to a lot of Indian skin found the glutathione group trended better on spot and tone measurements, but the difference from placebo didn't reach statistical significance for the group as a whole

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Note that with this method of delivery absorption occurs predominantly in the stomach to achieve therapeutic plasma levels, and overcomes otherwise insurmountable challenges of peptide absorption related to solubility, molecular size, and enzymatic degradation in the protease-rich environment of the small intestine (Buckley et al, 2018)

Ip, W., Wong, C