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Glu170 interacts with HEDS-derived GSSEtOH Next, we compared the steady-state kinetics of E170X mutants and wild-type ScGrx7 at variable HEDS and GSH concentrations

Hemin suppresses the TSS pathway CBS expression and interferes with de novo cysteine biosynthesis and GSH generation, leading to elevated oxidative stress

2.2 Parkinson's disease (PD) PD patients show exhaustive gut microbiome dysbiosis, such as reduced Prevotella and increased Enterobacteriaceae, which can be related to GI symptoms such as constipation (Hashish and Salama, 2023)

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GE Healthcare, Piscataway, NJ, USA) and imaged using a chemiluminescence imager (ChemiDoc