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In the context of GLP-1R agonists, GLP-1-expressing NTS neurons project to the LC [69], and administration of exendin-4 into this brain region robustly suppresses food intake and causes an aversive response in rats [91]

This has been seen in both immunocompetent and immunocompromised HBV transgenic mouse models

Women are twice as likely to have side-effects when taking GLP-1 receptor agonists including gastrointestinal symptoms such as vomiting

Nature 347 , 645 (1990)

Theyre also reshaping collective behaviorhow people eat, shop, move, perceive themselves, and make decisionswith significant implications for business leaders.