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Plume geometry testing is performed at the beginning of the lifestage and uses the same laser imaging infrastructure as spray pattern testing

10.7554/eLife.64140 eLife 17 BellM

Its activity profile is best understood as systems-level: published in vitro and in vivo work has documented effects on fibroblast proliferation, collagen and growth-factor receptor expression, endothelial migration, nitric oxide system signalling, and dopamine and serotonin pathway markers

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2 Materials and methods 2.1 Worms maintenance, mucus collection and hallachrome extraction Halla parthenopeia is a large marine annelid (up to 1 m in length) that burrows into the sandy bottoms of the Mediterranean