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In addition, some experimental and clinical data suggested that early intravenous supplementation with L-carnitine could improve survival in severe valproic acid -induced hepatotoxicity [5]

(3) In patients with AF, myocardial glucose uptake is decreased while metabolic activity is enhanced, accompanied by increased glycolytic activity and impaired mitochondrial function

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Many patients are on a combination of an SGLT2 inhibitor with a GLP-1 receptor agonist or tirzepatide (a dual agonist) and have incredible success without adverse reactions, but we are still figuring out the patient characteristics that would put them at higher risk of poor outcomes. Eli J