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Downregulating the expression of miR-23a and increasing the expression of the mitochondrial protective gene peroxisome proliferators-activated receptor- coactivator-1 (PGC-1) can exert an anti-apoptotic effect on human hepatocytes [34]

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Peroxisome proliferator-activated receptor (PPAR)- activation prevents diabetes in OLETF rats: comparison with PPAR- activation