PubMed alternative-therapies.com Not FDA approved and appears on lists of substances of concern for compounding and anti doping (WADA S0 unapproved class)
Psychiatrists and other mental health professionals sound the alarm that taking GLP-1s may provoke not only distress associated with uncomfortable side effects, but unhealthy eating habits
Safety research is mostly from adults
GLP-1 medications compared: Benefits and differences GLP-1 medications have rapidly become some of the most influential treatments for Type 2 diabetes and weight loss
For example, TRP channels, including TRPC1, TRPM2, TRPM3, TRPM4, TRPM7, TRPP1, TRPML1, and TRPML3 channels, expressed in human -cells at relatively high levels serve to enhance the intracellular Ca 2+ levels by either direct ways, or indirectly facilitating membrane depolarization, making Ca 2+ influx via voltage-gated Ca 2+ channels ( The electrical activity of -cells regulated by these ion channels is related to insulin release in response to glucose stimulation, especially for Kv2.1, which is crucial for shaping insulin secretion ( + currents largely carried by Kv2.1 channels, which are encoded by KCNB1 and abundantly expressed in -cells ( ATP channels and other K + channels are able to exhibit similar effects, possibly with varying potency, in tuning the insulin secretion of pancreatic -cells, due to these channels possessing similar regulatory actions in the electrical excitability
