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What the research shows: In the SURMOUNT clinical trials, patients taking tirzepatide lost an average of 2022% of their body weight over 72 weeks

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In this meta-analysis, the time span to the first occurrence of a confirmed MACE-4 (cardiovascular death, myocardial infarction, stroke, and hospitalized unstable angina) between study participants with T2D receiving tirzepatide was compared with the control groups receiving different standard therapy

Tirzepatide cardiovascular outcome trials are ongoing

It is currently under clinical investigation for the management of obesity and type 2 diabetes (as demonstrated in a phase 2 trial published in the New England Journal of Medicine), and as of the time of writing, it has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA)