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It has been shown in the literature (45, 46) that nuclear factor erythroid 2-related factor 2/Kelch-like ECH-associated protein 1 (Nrf2-keap1) is the main mechanism of resistance to oxidative stress, and demethylation of keap1 promoter activates the expression of Keap1 protein, which promotes the degradation of Nrf2 proteasome and attenuates Nrf2 activity, leading to the reduction of resistance to oxidative stress and ultimately causing the cataract occurrence

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If the answer is "yes" then pituitary and secreting organs holds hormone levels steady

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Lifestyle changes such as quitting smoking, maintaining a moderate weight, reducing stress, and limiting alcohol consumption can help reduce the risk of ED