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[8] The same copper that drives the biology is the primary safety liability systemically, and the therapeutic window enough copper to help, not enough to harm is uncharacterized for this route in humans
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[No author.] Are Analog Scales Accurate
9,10 Mitochondria, which are critical for cellular respiration and metabolism, suffer damage to their own mitochondrial DNA by the actions of reactive oxygen species and peroxynitrite compounds, and they have been directly implicated in the process leading to cessation of ATP synthesis
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