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The primary mechanisms through which Wegovy promotes weight loss include: Appetite suppression through central nervous system effects, reducing hunger and food cravings Delayed gastric emptying , prolonging satiety after meals Enhanced insulin secretion and reduced glucagon release, improving glycaemic control Reduced energy intake , creating a sustained caloric deficit These therapeutic effects can contribute to fatigue through several pathways

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Anecdotal reports vary, but some individuals mention mild headaches, anxiety, or an overstimulated feeling