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This contrasts markedly with full-length growth hormone, which can impair glucose tolerance and potentially precipitate or worsen diabetes

Although rare, serious side effects have been noted, with gallbladder disease and pancreatitis among the most concerning

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High cost and insurance restrictions are common, with many plans requiring step therapy, higher BMI, or documented inability to lose weight by other methods before approval. Do GLP-1 drugs replace the need for arthritis or autoimmune medications