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In den klinischen Programmen wurde Cagrilintid in einem wchentlichen subkutanen Schema mit schrittweiser Dosistitration angewandt mit dem Ziel, die gastrointestinale Vertrglichkeit zu verbessern: hnlich wie die GLP-1-Agonisten Semaglutide und Tirzepatide erfordert Cagrilintide in Studien eine langsame Titration zur Verbesserung der Vertrglichkeit

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The peptide's effects on memory consolidation appear mediated through enhanced hippocampal long-term potentiation (LTP), the neurophysiological basis of memory storage, with Dihexa treatment increasing both the magnitude and persistence of synaptic strengthening