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Prolonged hyperglycemia can lead to severe complications such as diabetic nephropathy, neuropathy, retinopathy, and cardiomyopathy (Janika et al., 2022

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In August 2025, Novo Nordisk announced that the FDA has approved WEGOVY as the first GLP-1 receptor agonist for adults with Metabolic Dysfunction-associated Steatohepatitis (MASH) who have moderate to advanced fibrosis, excluding cirrhosis, in combination with diet and exercise

Eur.J.Gen.Med 2009;6(2):7-15