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The HLCS gene is located on chromosome 21q22.13 and is composed of 19 exons that generate eight alternatively spliced mRNAs, seven of which encode the same 726 amino acid protein (isoform 1) and one which encodes a 873 amino acid protein (isoform 2)

However, prolonged elevations in cortisol are not healthy, so time could be another factor

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5 The impact and expression of the IGF family in neoplastic prostate cells and tissues During the transition from benign to malignant state in prostate cancer, several IGF family members change