Schreiner, B
Frequency of administration In the case wherein the patient's condition does not improve, upon the doctor's discretion the administration of the compounds is administered chronically, that is, for an extended period of time, including throughout the duration of the patient's life in order to ameliorate or otherwise control or limit the symptoms of the patient's disease or condition
Cell physiology 292 , C125136, doi: 10.1152/ajpcell.00247.2006 (2007)
Sheng R, Zhang Y, Sun W, Ji Y, Zeng M, Yao X, Dai Y
The dose-response curve between 8 and 12 mg shows diminishing returns, meaning 10 mg captures most of the benefit while potentially reducing some of the dose-related side effects seen at 12 mg