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Bioassay-guided isolation of the chloroform fraction yielded (E)-4-(3,4-dimethoxyphenyl) but-3-en-1-ol as the active compound (Ramadhan et al., 2020)

New England Journal Of Medicine *In a 68-week placebo-controlled study of 1,961 obese and overweight non-diabetic adults with weight-related conditions, those on semaglutide lost on average 14.9% of their weight as opposed to 2% of the placebo group

research is supported by funding from ZJU 100 Young Professor Project, Rut and Arvid Wolff Memorial Foundation (2023-02467), ke Wiberg Foundation (M19-0266), Fredrik and Ingrid Thuring Foundation (2019-00488)

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