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132 Even within a breed that may be considered healthy, inbreeding (mating of closely related animals) is associated with an increased risk of the development of genetic diseases

In a placebo group, the average weight loss was just under six pounds, or about 2.5%

Miyazawa T, Nakagawa K, Kudo M, Muraishi K, Someya K

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Blocking this process with FAK kinase inhibitors may stabilize sites of focal adhesions and explain the increase in FAK, paxillin, and dual FAK-paxillin containing focal adhesions we observed following treatment with high nanomolar to low micromolar doses of defactinib