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Because of this, oral sermorelin in the form of, say, a capsule, is not recommended as an effective treatment option due to its rapid degradation by digestive enzymes, resulting in extremely poor bioavailability

The most well-known is GLP-1 (glucagon-like peptide-1), which slows gastric emptying and reduces appetite

437 Selective reduction of cytosolic ME1 expression and enzyme activity significantly reduces GSIS and amino acid-stimulated insulin secretion (AASIS)

Vitamin B12 injections may offer a safer alternative for patients concerned about side effects