The induction of hepcidin expression in response to IL6 was demonstrated to be mediated by the Janus kinase 2/signal transducers and activators of transcription 3 (JAK2/STAT3) pathway [4648], while a potential interaction between STAT3 and BMP/SMAD signaling may be also involved in the induction of hepcidin under inflammatory condition [40, 49]
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International Journal of Molecular Sciences, 19(7), 1987.
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Pharmacol Rev 56(3):331349 Engelen M, Vanna R, Bellei C, Zucca FA, Wakamatsu K, Monzani E, Ito S, Casella L, Zecca L (2012) Neuromelanins of human brain have soluble and insoluble components with dolichols attached to the melanic structure