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Targeted drugs such as endothelin receptor antagonists and prostacyclin analogs can improve symptoms, but their high cost and limited reimbursement restrict accessibility in low-resource areas (Nathan, 2023

Elevated levels of ROS and oxidative damage markers have been detected in the brains and cerebrospinal fluid of MS patients [148]

Protective effects of genistein on myocardial injury in diabetic rats

Ex vivo analysis of plasma from volunteers following PYC administration revealed moderate inhibition of COX-1 and COX-2 activity, indicating potential anti-inflammatory and platelet-inhibitory effects (Schfer et al., 2006)

Only after 90 days will all the pre-existing red blood cells have expired, and be replaced by healthy ones