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Your brain starts sending the same hunger signals it sent before you ever started treatment, except now you have less body mass, which means your body perceives a caloric deficit and pushes even harder for you to eat

While current clinical candidates focus primarily on selective MC4R agonism for the limited treatment of genetic and hypothalamic obesity, 710GO appears to be the only current developmental program poised to address general obesity as a monotherapy

Wang RX, Yu CR, Dambuza IM, Mahdi RM, Dolinska MB, Sergeev YV, et al

PMID 27313432

Your results are permanent since the fat cells do not come back once they have been eliminated