The AMPK has a unique heterotrimeric structure consisting of one catalytic subunit () along with two regulatory subunits ( and ) (Garcia and Shaw, 2017)
IX-71 inverted microscope the pipette-to -bath DC resistance of patch electrodes ranged from 4.0 to 5.2 , and were filled with a internal solution of the following composition (in mM): 25 CsCl, 100 CSCH3O3S, 10 phosphocreatine, 0.4 EGTA, 10 HEPES, 2 MgCl 2) 0.4 Mg-ATP, and 0.04 Na-GTP
J Bone Min Res Off J Am Soc Bone Min Res
Cancer 11 , 886895 (2011)
Heme oxygenase 1 (HO-1) is an NRF2 target gene that prevents FH deficiency-mediated succinate stagnation through the heme synthesis and degradation pathway ( BEYOND REGULATING REDOX HOMEOSTASIS: NRF2 PROMOTES ANABOLIC PATHWAYS IN CANCERS In addition to coordinately activating the genes encoding detoxifying enzymes and antioxidant proteins, the constitutive accumulation of Nrf2 confers chemo- and radio-resistance for cancer cell survival