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doi: 10.1016/S1470-2045(21)00034-6

40,41 A study using nationwide registers in Nordic countries showed that with an additional adjustment for laboratory results (glycated hemoglobin, albuminuria, eGFR), there was no difference in the risk of AF between SGLT2i users and GLP-1RA users in Swedish cohort (HR=0.90 [95% CI: 0.79 to 1.01]) and in Danish cohort (HR=0.92 [95% CI: 0.79 to 1.08])

1,2 The only GST belonging to the pi class is GSTP1-1, an interesting enzyme that is mainly present in erythrocytes, brain, lung and skin

Lifestyle choices, skin type, pigmentation intensity, and the underlying reason for dark circles are all important factors

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