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PMID: 33132510

Here are a few reasons for this: Proteolysis (protein digestion): Protein digestion is likely to be impaired in hypothyroidism, but tends to be accelerated in hyperthyroidism

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Metzger WJ, Zavala D, Richerson HB, Mosely P, Iwamota P, Monick M, Sjoerdsma K, & Hunninghake GW (1987) Local allergen challenge and bronchoalveolar lavage of allergic asthmatic lungs

If you're experiencing side effects or struggling to remember your dose, your provider can recommend changes to timing or help you establish a routine