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The research trials used higher, weight-based doses under medical supervision

The company acknowledges that Mrkyl only seems to work for 7/10 people

It means that excess amounts are typically excreted through urine rather than accumulating to toxic levels , making vitamin B12 supplementation generally safe even at higher doses, though adverse reactions such as hypersensitivity or acneiform rash can occur rarely

22, 2016) concluded: Long-term use of metformin in DPPOS was associated with biochemical B12 deficiency and anemia