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This framing also explains why GLP-1s may be most effective early in the disease continuum, or as part of preventive strategies aimed at preserving cerebral blood flow, metabolic health, and mitochondrial resilience before irreversible neurodegeneration takes hold [14,15]

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Results suggest that sleep-dependent motor learning is associated with a large-scale plastic reorganization of memory throughout several brain regions, allowing skilled motor movements to be executed more quickly, more accurately, and more automatically following sleep