A review of GLP-1 agonist studies using the standard dose in high intracranial pressure reported: Patients should be counseled about the high likelihood of nausea and GI upset (diarrhea, vomiting, and constipation, delayed gastric emptying) especially in the first 48 weeks of therapy
Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse
Researchers found that the safety profiles of both drugs were generally consistent with the GLP-1 receptor agonist class
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The FDA has published specific concerns for this category, including multiple adverse event reports, some requiring hospitalisation, that may relate to dosing errors