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For someone who has battled significant weight challenges or found other methods ineffective, the higher weight loss potential of tirzepatide might be a compelling reason to start a conversation with a provider

[56] Serum haptocorrin binds 80-90% of circulating B 12 , rendering it unavailable for cellular delivery by transcobalamin II

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After four weeks without treatment, exposure to semaglutide is markedly reduced, requiring careful consideration when restarting