After treatment , common effects include bruising at injection sites (10-15% of clients), temporary fatigue, and increased urination
Typically, they might be administered once or twice a week over a period to achieve desired antioxidant and detoxication benets
This may include swelling, pain or discomfort, discoloration, or a rash
Acetaminophen-related ALF was the most common etiology Return to top The physiology of acetaminophen overdose 2 Acetaminophen Metabolism Acetaminophen is metabolized through 3 different pathways: 42% to 67% undergoes glucuronidation and is excreted in urine 26% to 36% undergoes sulfation and is excreted in urine 5% to 8% passes through the cytochrome P-450 pathway producing a potentially hepatotoxic metabolite, N-acetyl-p-benzoquinone imine (NAPQI) In normal dosing, NAPQI is conjugated with the antioxidant, glutathione, and excreted in urine Return to top Mechanism of Action Overdose depletes the available glutathione and unbound NAPQI destroys liver cells
Quest-ce que le glutathion ? Le glutathion est une molcule tripeptidique naturelle compose de trois acides amins : la cystine, l'acide glutamique et la glycine
